Cordies Cable Organizers: These might look more like brass knuckles or some other handheld weapon than a device for keeping your wires in place, but they'll actually hold USB and charging cables wherever you want them. No more hunting for that iPod cable; just insert the tip into one of four loops and you'll always know where it is. Not only does this organizer keep cables in place, it also protects them from the unnecessary damage incurred when you pull one wire out of a whole nest of them.
Command Adhesive Cord Clips: These versatile little guys give you essentially unlimited control over where your cords go. Not only can you coil up your unused cords and loop them through these hooks on the edge of your desk, your wall, wherever, you can also thread cables through multiple hooks to keep them in place while you're using them. Create a whole network of wires if you like. Divert them wherever you want.
Ballou Projects Power Lines: These are pretty much the classiest option for organizing cables ever in the history of all things. Instead of hiding your wires away where you can't see them, embrace their display by looping them across two miniature pylons. Suddenly, your desk isn't just a mess of cables and gadgets. It's a tiny landscape complete with tiny power lines. Complete the look with a city built from your Lego collection if you like. It's your desk.